The Antiglobulin Test
This test utilizes antihuman globulin (AHG)
reagents to cross link and connect adjacent
red blood cells sensitized with IgG and/or
complement.
Antihuman globulins
are antibodies
directed against human globulins such as IgG
and complement components.
◦Anti-IgG would attach by
their Fab pieces to the
heavy or light chain of the bound IgG molecules,
resulting in visible agglutination.