Which of the following is a piece of evidence that supports that circulating levels of serotonin are decreased in either anxiety or affective disorders?
A) Drugs that inhibit tyrosine hydroxylase activity improve mood.
B) Tricyclic antidepressant administration decreases CSF serotonin levels in those with OCD.
C) Esketamine acts as a rapid-acting antidepressant.
D) Patients with anxiety disorders report high placebo symptoms
E) Monoamine Oxidase (MAO) Inhibitors improve mood.
F) Serotonin transporter expression is decreased in individuals with OCD.