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Does the abnormal chromosome have a pericentric or paracentric inversion? Draw a sketch showing how these two chromosomes would pair during prophase I of meiosis. What would be the result if a crossover occurred between N and O within the inverted region?

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Answer:

The result of the possible crossover is shown below on explanation

Explanation:

If two chromosomes have the following order of genes:

Normal: J K L M centromere N O P Q R

Abnormal: J K P O N centromere M L Q R

Then Pericentric crossing over will result in:

J K L M centromere N O P Q R,

J K L M centromere N O P K J (duplication of J K and deletion of Q R)

R Q P O N centromere M L Q R (duplication OF R Q, deletion of J K)

J K P O N centromere M L Q R

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