Answer:
Labeling involves covalent modification of the enzyme
Explanation:
Labelling is a method which is used to label a marker molecule in a mixture of substance. When the molecular markers which act as a label are attached to the enzyme is known as the enzyme labelling.
The enzyme labelling is used in many areas of biology and biochemistry like it is used in the blood test in the medicine and in knowing the structure of the active site of an enzyme.
To know the active site of an enzyme, the label binds to the active site which involves he covalent modification with the enzyme and is irreversible.
Thus, selected option is correct.