Suppose a point mutation, such as a change from an adenine to a guanine, occurs in the genome of a human sperm cell. The mutation could occur in any region of a gene. The effect of the mutation on the phenotype of the offspring will be determined by where the mutation occurs and its effect on the final gene product. In which of the following scenarios could the mutation alter the phenotype of the offspring? A. The mutation occurs in the promoter and affects the rate of gene transcription. B. The mutation results in a new, dominant allele The mutation occurs in a portion of an intron not responsible for exon splicing.C. The mutation occurs in a gene that controls development and alters differentiation of a cell type during development. D. The mutation occurs in a codon and alters the function of the final protein e mutation occurs in a codon, and the amino acid sequence of the final protein is unchanged.

All the above things will change the ultimate expression or phenotype by altering the proteins. Choices B, C, and D will all change the outer functioning.

Choice A only affects the rate of transcription, so it may go faster or slower, but the end product will be the same.

This part that doesn't look like it's one of the choices ("The mutation occurs in a portion of an intron not responsible for exon splicing.") would not affect phenotype, because introns are removed before the RNA is sent out.

Choice E says that the amino acid sequence is unchanged, meaning the protein final product will be the same and the expression will not change.