Yes, it is possible for the baby to have cystic fibrosis if the mother has one or two recessive genes or carries the gene if Mr. Odenbach is pure recessive.
Cystic fibrosis is an autosomal recessive disorder and can affect individuals when both alleles are affected. The presence of even one normal copy of the allele does not result in disease.
In this case,
- Mr. Odenbach has both alleles recessive that means two recessive genes
- Let's take the cystic fibrosis allele as "c". So, dominant allele "C" will form a normal phenotype
- The genotype of Mr. Odenbach is - cc and gametes will carry genes c and c
- As it is known that in child genes come from both parents, therefore, it is confirmed that baby will have at least one recessive gene.
In the case of heterozygous or carrier wife, the baby would have cystic fibrosis:
- Condition 1. If the wife is heterozygous
C c
c Cc cc
c Cc cc
half carrier and half affected
- Condition 2. if the wife is normal
C C
c Cc Cc
c Cc Cc
all carries gene but not affected
- Condition 3. if the wife also have cystic fibrosis
c c
c cc cc
c cc cc
all babies have cystic fibrosis
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