(c) Researchers analyzing the SIRT3 gene sequence engineer a SIRT3 gene that is identical to the normal gene
except that a single nucleotide has been deleted from the 5' end of the second exon of the gene; the deletion does
not affect splicing. The researchers
introduce this gene into normal stomach cells to determine how the primary
AND tertiary structures of the protein expressed from the engineered SIRT3 gene will compare with the protein
expressed from the normal SIRT3 gene in these cells. Predict the results of this experiment. The researchers
claim that the data in Figure 3 provide evidence that the stomach cancer cells
perform fermentation to a greater
extent than do normal stomach cells. Provide reasoning to justify the claim. Based on the information provided,
predict the effect on the ratio of NADH/NAD+ in the cells treated with the compound that blocks the electron
transport chain compared with similar cells not treated with the compound.

Question

25-02-2022
Biology

contestada

(c) Researchers analyzing the SIRT3 gene sequence engineer a SIRT3 gene that is identical to the normal gene
except that a single nucleotide has been deleted from the 5' end of the second exon of the gene; the deletion does
not affect splicing. The researchers
introduce this gene into normal stomach cells to determine how the primary
AND tertiary structures of the protein expressed from the engineered SIRT3 gene will compare with the protein
expressed from the normal SIRT3 gene in these cells. Predict the results of this experiment. The researchers
claim that the data in Figure 3 provide evidence that the stomach cancer cells
perform fermentation to a greater
extent than do normal stomach cells. Provide reasoning to justify the claim. Based on the information provided,
predict the effect on the ratio of NADH/NAD+ in the cells treated with the compound that blocks the electron
transport chain compared with similar cells not treated with the compound.

Respuesta :

Otras preguntas

When calcium carbonate is added to hydrochloric acid, calcium chloride, carbon dioxide, and water are produced. CaCO3(s) + 2 HCl(aq) → CaCl2 (aq) + H2O(1) + CO2

simplify 5(6x+9) using the distributive property

The DNA of the young dragons was analyzed. All offspring were homozygous at all loci. They were not identical clones of their mother: their genetic makeup was d

Two related misconceptions about photosynthesis and cellular respiration are that only plants perform photosynthesis and that cellular respiration is performed

Which two of the following advances did Europeans borrow from China?

Given the function f(x) = 4(2)x, Section A is from x = 1 to x = 2 and Section B is from x = 3 to x = 4. Part A: Find the average rate of change of each section.

All of the following are benefits of following the ________ approach to target market selection: a strong knowledge of the segment's needs, a strong market pres

Which postulate proves these two triangles are congruent ?

Via Gelato is a popular neighborhood gelato shop. The company has provided the following data concerning its operations: Fixed Element per Month Variable Elemen

The magnetic field at the earth's surface can vary in response to solar activity. During one intense solar storm, the vertical component of the magnetic field c

luisvaschetto luisvaschetto · Answer 1 · 2022-03-03T13:07:15+01:00

It is expected that this single nucleotide deletion does not affect the functioning of the protein since this modification didn't alter gene splicing. Cancer cells may have high metabolic activity.

The metabolic characteristics of cancer cells

Cancer cells exhibit more plastic phenotypes than normal cells, thereby mutations of genes associated with metabolism in cancer cells may lead to a selective advantage to generate ATP and thus increase their metabolic rate.

In consequence, it is expected that stomach cancer cells can perform fermentation at a faster rate than normal cells because they may exhibit high metabolic activity.

Finally, the NADH/NAD+ ratio will be decreased in cells treated with a compound that blocks the electron transport chain because NAD+ is reduced to NADH during this step of cellular respiration.

Learn more about cancer cells here:

https://brainly.com/question/373177