Based on the pedigree, the percentage of offspring who are carriers of sickle cell anemia is 50%.
What is sickle cell anemia?
Sickle cell anemia is a disease of the red blood cells in which mutations in the haemoglobin results in inability of the red blood cells to carry oxygen efficiently to the cells.
Based on the pedigree chart, the carriers of sickle cell are those that are half shaded black.
Two out of four of the offspring are shaded this way.
Percentage = 2/4 × 100% = 50%.
Therefore, the percentage of offspring who are carriers is 50%.
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