In a holoenzyme, inorganic ions required for the complete structure of the enzyme that is not incorporated into the enzyme structure are called coenzymes.
The protein portion of a holoenzyme (i.e., a catalytically active enzyme) is called a coenzyme.
A coenzyme is a non-organic compound needed for the enzymes to have catalytic activity.
Inorganic ions are cofactors that may act during chemical reactions by activating the enzyme catalytic activity.
In conclusion, in a holoenzyme, inorganic ions required for the complete structure of the enzyme that is not incorporated into the enzyme structure are called coenzymes.
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