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Phosphofructokinase is an enzyme that acts on fructose 6-
phosphate at an early step in glucose breakdown. Regulation of this enzyme controls
whether the sugar will continue on in the glycolytic pathway. Considering this graph,
under which condition is phosphofructokinase more active? Given what you know about
glycolysis and regulation of metabolism by this enzyme, explain the mechanism by which
phosphofructokinase activity differs depending on ATP concentration. Explain why it
makes sense that regulation of this enzyme has evolved so that it works this way.

Phosphofructokinase is an enzyme that acts on fructose 6 phosphate at an early step in glucose breakdown Regulation of this enzyme controls whether the sugar wi class=

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phospare at an early step in glucose breakdown regulation of this enzyme control and under which condition more active.

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