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Voltage-gated calcium ion channels that function in neurotransmission are primarily found on the: excitable cells
A neurotransmitter is the body’s chemical messenger. They are molecules that transmit signals from neurons to muscles, or between different neurons. The transmission of signals between two neurons occurs in the synaptic cleft.
The electrical signals that travel along the axon are briefly converted into chemical signals through neurotransmitters.
Voltage-gated calcium (Ca2+) channels are key transducers of membrane potential changes into intracellular Ca2+ transients that initiate many physiological events. There are ten members of the voltage-gated Ca2+ channel family in mammals, and they serve distinct roles in cellular signal transduction.
They are found in excitable cells, not only in motor neurons but also in other types of excitable cells .
Voltage-gated calcium channels are important mediators of depolarization-evoked release of neurotransmitters. To ensure efficient coupling of calcium influx to rapid vesicle release, calcium channels must be localized within the active zones of presynaptic nerve terminals
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