The group of vascular disorders that are marked by blood vessel necrosis and inflammatory injury is Cutaneous necrotizing vasculitis.
Vasculitis involves inflammation of the blood vessels. The inflammation can cause the walls of the blood vessels to thicken, which reduces the width of the passageway through the vessel. If blood flow is restricted, it can result in organ and tissue damage. There are many types of vasculitis, and most of them are rare.
Cutaneous necrotizing vasculitis is a not uncommon disorder characterized by an inflammation of the blood vessel walls and skin lesions. These skin lesions may be flat and red (macules), nodules, or more substantial hemorrhages under the skin (purpura).
Colchicine, hydroxychloroquine, dapsone, or a short course of low-dose corticosteroids can be tried. Sometimes, stronger immunosuppressants (eg, azathioprine, methotrexate) are used, particularly if lesions ulcerate or if corticosteroids must be taken indefinitely to control symptoms.
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