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Amniocentesis is generally recommended for pregnant women with family history of birth defects or genetic abnormalities or previous child with genetic disease.
Amniocentesis is an invasive prenatal test to detect genetic disorders. The Amniotic fluid is water like protective fluid surrounds the fetus. This yellowish fluid also carries the genetic information of the fetus.
The test procedure involves the collection of a small amount of amniotic fluid using a fine needle and screening for chromosomal abnormalities. The commonly used screening techniques are karyotyping, FISH and microarray analysis.
This procedure is usually performed between 15 to 18 weeks of pregnancy, only with physician recommendation because procedure can cause injury to the foetus and mother, infection or preterm labour and potential risk of causing miscarriage.
It is commonly performed to detect downs syndrome, tay-sachs syndrome, sickle cell anemia, cystic fibrosis, muscular dystrophy, etc.
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