Diffusion through canaliculi is the mechanism through which nutrients are brought to spongy bone.
What is the canaliculi in bone?
Bone canaliculi are tiny canals that run through the dense matrix of the bone, containing the dendrites of osteocytes, and filled with an ion-rich interstitial fluid. Fluid flow and electrochemical phenomena coexist in very tiny (a few hundred nanometers in diameter) canals. The canaliculi function as a conduit for osteocyte communication, the removal of cellular wastes, and the delivery of nutrients via blood vessels.
Osteocytes maintain contact with one another and with cells on the surface of the bone thanks to gap junction-coupled cell processes that travel through the matrix through tiny passageways called canaliculi. These canaliculi link the lacunae, which contain cell bodies, to other cells and to the outside world.
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