Contractility is the characteristic of heart function most drugs focus on improving for heart failure clients have distinct signs and symptoms associated with the disease.
The innate ability of the heart muscle to contract is known as Myocardial contractility. According to Starling's Law, the heart will eject a greater stroke volume at greater filling pressures.
The factors which affect contractility are calcium concentration, temperature. Endurance training improves cardiomyocyte contractility.
A change in contractility also leads to a change in blood pressure, a decrease in cardiac contractility causes a decrease in stroke volume and therefore cardiac output. Consequently, the patient's blood pressure may fall to dangerously low levels.
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