One can think of Alzheimer's disease as the deterioration and breakdown of ACh-producing neurons.
Acetylcholine (ACh) is an organic chemical that serves as a neurotransmitter in the bodies and brains of numerous animal species, including humans. It is an ester of acetic acid and choline, which is how its name was derived from its chemical composition. Cholinergic refers to bodily regions that use or are impacted by acetylcholine. Cholinergic and anticholinergics are terms used to describe substances that alter the cholinergic system's overall activity. The neurotransmitter that is used at the neuromuscular junction, or the chemical that is released by motor neurons of the nervous system to activate muscles, is acetylcholine. Because of this characteristic, cholinergic system-interfering drugs may cause very dangerous side effects, such as convulsions and paralysis. Both as an internal transmitter for the sympathetic nervous system and as the end product released by the parasympathetic nervous system, acetylcholine functions as a neurotransmitter in the autonomic nervous system.
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