The disease outbreak that resulted in a sharp decline in the population of the indigenous peoples was one of the short-term repercussions of the Columbian exchange.
Europeans sought naval routes to the Far East in the 15th and 16th centuries. To reach China, Japan, the Spice Islands, and India, Columbus looked for a new route. If he could only reach these nations, he could bring back valuable cargoes of spices and silks.
In 1492, 1493, 1498, and 1502, the explorer Christopher Columbus conducted four voyages from Spain across the Atlantic Ocean. He was adamant about locating a straight water passage from Europe to Asia, but he was never successful. Instead, he found the Americas by accident.
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