Tryptophan metabolism is directly involved in B vitamins such as vitamin B2, niacin, and vitamin B6, and indirectly by vitamin B1 and pantothenic acid.
Bacterial vitamin B2 is synthesized from guanosine triphosphate (GTP) and D-ribulose-5-phosphate (54). Bacterial vitamin B2 exists as free riboflavin and is directly absorbed in the colon, converted to FAD or FMN, and distributed throughout the body as described above.
B vitamins also help make hemoglobin, a protein that allows red blood cells to carry oxygen from the lungs to each cell.
Tryptophan (symbol Trp or W) is an α-amino acid used in protein biosynthesis. Tryptophan contains an α-amino group, an α-carboxylic acid group, and an indole side chain, making it a polar molecule with nonpolar aromatic beta-carbon substituents.
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