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trematol is a metabolic poison derived from the white snake root. cows eating this plant concentrate the poison in their milk. the poison inhibits liver enzymes that convert lactic acid to other compounds for metabolism. why does physical exertion increase symptoms of poisoning by trematol? why does the ph of the blood decrease in a person who has digested trematol?

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cenonjeric3

Here are the answers to the questions respectively:

  • Physical exertion increase symptoms of poisoning by trematol because the generation of lactic acid through fermentation, and when liver enzymes are inhibited, the accumulation of lactic acid lowers blood pH.
  • The pH of the blood decrease in a person who has digested trematol because exercise stimulates metabolism, and blood pH rises as a result of the electron transport chain pushing H+ out of the mitochondria.

A metabolic poison called trematol is made from the white snake root. The toxin is concentrated in the milk of cows that consume this plant. The toxin prevents the liver's enzymes from metabolizing lactic acid into other chemicals.

Our cells make lactic acid through a process known as fermentation when there is not enough oxygen present. Particularly in our muscles, the pyruvate from glycolysis is converted to lactic acid to replenish NAD+ from NADH, allowing glycolysis to continue producing ATP. This explains why exercise makes the symptoms worse.

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