Respuesta :
The nuclear pore complex is responsible for selecting and transporting only properly processed eukaryotic mRNAs into the cytoplasm.
How is the nuclear pore complex formed?
- It is separated from the rest of the cell by a boundary called the nuclear envelope, which consists of a two-layer membrane. All transport into and out of the nucleus must occur through channels within the envelope formed by large assemblies of proteins (nucleoporins) called nuclear pore complexes. Each NPC contains at least 456 individual protein molecules and is composed of 34 different nucleoporin proteins.
Where is the nuclear pore complex located and their function?
- The nuclear pore complex (NPC) is a macromolecular protein assembly embedded in the double lipid bilayer of the nuclear membrane and is the single gateway for macromolecular transport between the nucleus and cytoplasm. The structure of NPCs (cylindrical ring-like structures lined with nucleoporins that can bind transport factors) determines their transport function.
- Each nuclear pore allows the free diffusion of small molecules and ions into and out of the nucleus. Nuclear pores also allow desired proteins to move from the cytoplasm to the nucleus if they carry a special sequence that indicates they belong to the nucleus.
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