A separate type of antibody with a different antigen-binding location is produced by each B cell. A naive or memory B cell multiplies and develops into an effector cell that secretes antibodies when it is triggered by an antigen (with the help of a helper T cell).
Antigen attachment to the B cell receptor (BCR) starts the process of B cell activation and sets off a series of signalling cascades that eventually result in B cell activation.
Antigens attach to receptors on the cell surface of B-cells, activating them and causing them to divide and proliferate. Some B-cells that have been stimulated develop into plasma cells, which release antibodies. Others develop into long-lived memory B-cells that can be activated later.
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