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G protein would constantly be in motion. G proteins are a family of proteins that serve as molecular switches within cells, they are engaged in the transfer of signals from the outside of the cell to its interior.

G proteins are trimers made up of three distinct subunits that activate adenylyl cyclase. Alpha, beta, and gamma subunits are the names of these. Gs is the name of the nucleotide-binding site on the alpha subunit. Adenylyl cyclase is activated when GTP binds to Gs, activating it in turn. When GDP binds to the nucleotide-binding site of G-protein, it becomes inactive.

When a signalling molecule like adrenaline binds, it makes it easier for GTP to replace the bound GDP and change the Gs into its active form. The beta and gamma Gs subunits separate from the alpha subunit as Gs is activated. Adenylyl cyclase is then activated by the Gs after it has bound GTP and its alpha subunit.

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