Smallpox lesions are solid, deep, and domed-shaped, while chickenpox lesions are small, raised, and filled with a clear fluid. Smallpox lesions also feature a center dimple. The varicella-zoster virus causes chickenpox while the variola major virus is responsible for smallpox.
In 1977, smallpox was last seen in a naturally occurring situation. Smallpox has been eliminated, according to the World Health Organization, by 1980. There is no proof of naturally occurring smallpox transmission at this time. Smallpox, which was caused by the variola virus, was a serious infectious disease before it was eradicated. It spread from one person to another because it was contagious. Fever and a characteristic, developing skin rash were symptoms of smallpox in sufferers.
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