A membrane produces an H+ channel when the protein gramicidin is incorporated into it, making the membrane highly permeable to protons (H+ ions).
Gramicidin is a polypeptide antibiotic that, like nystatin, creates tiny pores in cell membranes but only permits the transport of monovalent cations while blocking anions. The cation selectivity sequence of gramicidin in lipid bilayers and cell membranes is identical.
Normally, DNA damage results in phosphorylation, which creates space surrounding broken DNA so that repair mechanisms can function.
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