If the frequency of pku, an autosomal recessive disease, is 1% in males, what is the frequency of females with pku?.

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24-11-2022
Biology

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If the frequency of pku, an autosomal recessive disease, is 1% in males, what is the frequency of females with pku?.

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luisvaschetto luisvaschetto · Answer 1 · 2022-11-28T18:32:14+01:00

If the frequency of PKU, an autosomal recessive disease, is 1% in males, then the frequency of females with PKU is expected to be equal (1%) in females since an autosomal recessive disease affects an autosomal (non-sexual) chromosome.

What is an autosomal recessive disease?

An autosomal recessive disease is any genetic condition associated with the transmission of gene variants or alleles present on autosomal chromosomes, which are non-sexual chromosomes inherited in equal proportion in both sexes (i.e, in females and males).

The proportion of autosomal recessive diseases is expected to be roughly equal both in females and males due to these chromosomes are present in the same proportion for both.

Therefore, with this data, we can see that autosomal recessive diseases are conditions inherited by the transmission of defective alleles present in the autosomal chromosomes, which are non-sexual chromosomes that are inherited in equal proportion regardless of the sex (i.e. both in females and males).

Learn more about autosomal recessive diseases here:

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