People who are heterozygous for sickle cell anemia have the “sickle cell trait.” This is a much milder form of the disease. Looking at the image below, what can you infer about having the sickle cell trait and malaria?

A. The genotype for the sickle cell trait is manipulated by natural selection.

B. It is better to have the sickle cell trait in areas where malaria is uncommon.

C. Having the sickle cell trait in regions where malaria is not prevalent carries a higher fitness.

D. Having the sickle cell trait in regions where malaria is common carries a higher fitness.