By changing the body’s supply neurotransmitters. Drugs change neurotransmission by working together with molecular components of the sending and receiving method excluding receptors. For example, cocaine fastens to the dopamine transporter, the molecular conduit that draws free-floating dopamine out of the synapse and back to the sending neuron. On condition that cocaine occupies the transporter, dopamine cannot re-enter the neuron. It builds up in the synapse, stimulating receiving-neuron receptors more copiously and creating much greater dopamine impact on the receiving neurons than occurs naturally.
