An enzyme may catalyze a reaction by stressing or destabilizing the bonds of the substrates. this critical point in the enzymatic reaction is known as the

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Catalysis An enzyme may catalyse a reaction by stressing or destabilizing the bonds of the substrates. This point in the enzymatic reaction is known as the Transition State.  An enzyme can couple a nonspontaneous reaction to a spontaneous reaction so that anabolic processes will occur.