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Am certain that a human gamete produced by such a nodisjunction could have a chromosome number of 43. Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division. There are three forms of nondisjunction: Failure of a pair of homologous chromosomes to separate during meiosis I, failure of sister chromatids to separate during meiosis II, and failure of sister chromatids to separate during mitosis.

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