Serine has pka1 = 2.21 and pka2 = 9.15. use the henderson-hasselbalch equation to calculate the ratio neutral form/protonated form at ph = 3.05.

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26-04-2018
Chemistry

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Serine has pka1 = 2.21 and pka2 = 9.15. use the henderson-hasselbalch equation to calculate the ratio neutral form/protonated form at ph = 3.05.

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ChemistryHelper2024 ChemistryHelper2024 · Answer 1 · 2018-05-07T22:14:08+02:00

ChemistryHelper2024 ChemistryHelper2024

07-05-2018

Calculate the ratio by using Henderson-Hasselbalch equation:

pH = pKa + log [neutral form] / Protonated form

3.05 = 2.21 + log [neutral form] / [Protonated form]

3.05 - 2.21 = log [neutral form] / [Protonated form]

0.84 = log [neutral form] / [Protonated form]

[neutral form] / [protonated form] = anti log 0.84 = 6.91

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